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Clinical Hematology & Medical Oncology

Head of the Department

Dr. Chandran K Nair

Professor & HOD
Phone - 0490 23 99 245
Email - chmogmcc2019@gmail.com

Divisions
Sl Name View
1 Clinical Hematology Division Read More
2 Medical Oncology Division Read More
3 Paediatric Oncology Division Read More

The Department of CHMOG has three divisions - namely, Clinical Hematology division, Pediatric Oncology division and Medical Oncology - solid tumor division. Clinical Hematology division focuses on evaluation and treatment of benign hematological disorders in all age groups and malignant hematological disorders in patients aged 15 and above. This division also provides Hematopoietic stem cell transplantation for benign and malignant disorders in both adults and in children.

Medical oncology division deals with comprehensive evaluation and medical treatment of various types of solid tumors in adults with chemotherapy, immunotherapy and targeted agents.

Spectrum of cases seen in Medical Oncology division include Breast cancer, Gastrointestinal cancers, Lung cancer, Head and Neck cancers, Gynaecological cancers, Endocrine cancers, Thoracic cancers, Genitourinary cancers, Brain tumors and cancers of bone and soft tissues. This division is well versed in administration of intraperitoneal and intravesical chemotherapy.

Paediatric oncology division at MCC-PGIOSR caters to management of childhood cancer in children below 15 years of age.The spectrum of childhood cancers that are managed in this division include leukemias - ALL & AML, Lymphomas - Hodgkin and Non-Hodgkin lymphomas, Solid tumors - Wilm’s tumor, Neuroblastomas, Hepatobalstomas, Bone tumors (Ewing sarcoma and Osteosarcoma), Brain tumors (Medullobastomas, optic pathway gliomas and other astrocytomas), Retinoblastomas, soft tissues sarcomas (RMS and NRSTS), Germ cell tumors, LCH.

Sl Faculty Name Designation
1 Dr. Chandran K Nair Professor & HOD
2 Dr. Praveen Kumar Shenoy Associate professor
3 Dr. Jithin T K Assistant Professor
4 Dr. Shoaib Nawaz.P.N Assistant Professor
5 Dr. K G Gopakumar Assistant Professor
6 Dr. Nandini Devi R Assistant Professor
7 Dr. Abhilash Menon Assistant Professor
8 Dr. Arun Krishnan M P

  • Dr Jeny Presented the topic - “AIHA 
  • Dr Chandran K Nair Presented the topic “FL - When and holo to Rx 
  • Dr Vineetha presented the topic “Approach to bleeding  in a child “
  • Dr Rayeesa presented the topic “Case of  factors  12 Deficiency” 
  • Dr Eswar Presented the topic “ Case  of APS in child”
  • Dr Jeny Presented the topic”Case of GT”
  • Dr Eswar presented the topic “ITP Diagnosis and Treatment “
  • CPC Meeting  discussion  held  on 20.04.2022
  • Dr K G Gopakumar presented study protocol “Compliance to vaccination in childhood cancer survivors & knowledge attitude and practice among parents” and “Intrathecal administration of drugs during treatment of pediatric acute leukemia; practices among clinicians in India” on 06/04/22
  • Dr K G Gopakumar presented topic “Management of VTE in pediatric cancer; revisiting evidences” on 28/04/22
  • Dr Vineetha and Dr Gopakumar presented the topic “Protocol Presentation “
  • Dr Jeny Presented the topic “ Febrile neutropenia OP  Management “
  • Dr Nandini Devi Presented the topic “High Risk APML Rx”
  • Dr Eswar Presented the topic I.P Rx of  FN”
  • Dr Vineetha Raghavan Presented the topic “Rx of Relapsed FL”
  • Mortality meeting discussion  was held  on 26.05.22
  • Mortality meeting discussion  was held  on 31.05.22
  • Mortality meeting discussion  was held  on 1.06.2022
  • Mortality meeting discussion  was held  on 2.06.2022
  • Dr Arun PN  Presented the  topic “RT fields in lymphoma “9.06.22
  • Mortality meeting discussion  was held  on22.06.2022
  • Dr Manuprasad presented the topic “Primary CNS lymphoma 23.06.22
  • Dr Chandran K Nair Presented the topic “HL-guideliner “30.06.22
  • Dr Jithin T.K presented the topic “Well baby clinic”
  • Dr Eswar presented the topic “Who classification (MDS)risk  stratification  MDS
  • Dr Vineetha Raghavan presented the topic “Irb protocol  presentation 
  • Dr Praveen presented the topic “Incident report “
  • Dr Jeny Presented the topic “Protocol presentation “
  • Dr Sharath presented the topic “Antibiogram Part-1
  • Dr Praveen Kumar Shenoy “Journal club
  • Dr Jeny presented the topic “IWG criteria in multiple myeloma “
  • Dr Manuprasad Presented the topic “Protocol Presentation “
  • Mortality meeting presented on 24.08.22
  • Dr Eswar Presented to the topic “Case Presentation “
  • Dr Praveen Kumar Presented to the topic “Protocol presentation “
  • Dr Sharath Presented to the program “Antibiogram “
  • Transplant Board meeting  was held on 21.09.22
  • Mortality meeting discussion  was held  on 21.09.22
  • Department Mortality meeting was held on 28.09.22
  • Dr Sharath presented the topic “Polymyxine”
  • Transplant Board meeting held on 19.10.22
  • Dr Priya presented the topic  Diagnosis of systemic function infection  in patients with neutropenia 
  • Dr Priya presented the topic “Rx of systemic fungal infection in patient with neutropenia “
  • Dr Vineetha took class on the topic “haemato-oncology - an overview" for doctors from Primary Health Centers on October 21st and 28th.
  • Transplant  board meeting  held on 2.11.22
  • Dr Praveen Presented the topic “infertility in  Hemato oncology patients “
  • Dr Chandran K  Nair Presented the topic “CML , EXISTING Rx  and some new developments 
  • Dr Vivek Presented the topic  “Iron absorption “
  • Dr Chandran K Nair Presented the topic “Ph + ve  ALL 
  • Mortality meeting held on 3.11.22
  • Dr Gourav presented the topic “Structure of Hb 
  • Transplant board meeting was held  on 7.12.22
  • Dr Jithin T.k presented the topic “Protocol presentation”
  • CPC meeting was held on 7.12.22
  • Dr Gopakumar presented the topic “ MRD in pediatric ALL”
  • Dr Manuprasad Presented the topic “ Chimerism in  POST allo HSCT”
  • Mortality meeting was held On 21.12.22
  • Dr Gourav Presented the topic “ Case presentation 
  • Mortality meeting was held on 23.12.2022
  • Dr Vivek presented the topic “ Pathology of IDA “
  • Dr Praveen Kumar presented the topic “Journal club “
  • Transplant board meeting was held  on 11.1.23
  • Dr Priya Presented the topic”Rx of shock “
  • Mortality meeting was held  on 18.01.023
  • Mortality meeting was held  on 18.01.2023
  • Dr Gourav presented the topic “Hematopoiesis”
  • Case presentation 23-01.2023
  • CPC (Hemato molecular  path)
  • Dr Francis presented the topic “Pathophysiology of hemophilia”
  • Lung infections in  hemato-oncology 
  • Dr Vivek presented the topic “Pathogenesis of APLA”
  • Dr Chandran K Nair Presented the topic “Role of Mrd in adult ALL”
  • Case presentation held on 2.02.2023
  • Transplant board meeting held on 8.02.2023
  • Dr Nikhil presented the topic “PET CT  basics 
  • Dr Preethi presented the topic “Transplant of APLA syndrome”
  • Case presentation held on held on 9.02.2023
  • Department mortality meeting  held on 15.02.2023
  • CPC meeting held on 15.02.2023
  • Dr Gourav Case presentation held on “15.02.2023
  • Dr Vivek Case presentation held on 13.02.2023
  • Dr Gourav Presented the topic “Journal club “
  • Dr Francis Presented the topic “RX Hemophilia without …………
  • Dr Vivek Presented the topic “study protocol presentation 
  • Dr Preethi case presentation held on 23.02.2023
  • Transplant board meeting was held  on 1.03.2023
  • Dr Chandran K Nair presented the topic “Ph+ve ALL Rx “
  • Dr Vivek Presented the topic “TTP- pathophysiology “
  • Dr Jithin T.K presented the topic “St Jude Global ID program - Lessons learned”
  • Dr Jithin T K presented 2 research protocols
  • Mortality meeting was held on 15.03.2023
  • Dr Preethi presented the topic “Protocol presentation “
  • Dr Vivek Presented the topic “Case presentation “
  • Dr Sharath presented the topic “HIC practices”
  • Dr Preethi presented the topic “Rx of TTP”
  • Dr Nikhil presented the topic “PET CT part2”
     

  • Dr Vineetha presented the topic “ Approach to bleeding child” at IMA Clinical meeting on April 20th and at IAP Thalassery meeting on April 30th as part of World hemophilia day celebrations.
  • Dr Jeny presented a case “ Case of Glanzmann Thrombasthenia” at IMA Clinical meeting on April 20th
  • Dr Eswar presented a case “ Case of APS in a child” at IMA Clinical meeting on April 20th
  • Dr Rayeesa presented a case “ Case of factor 12 deficiency” at IMA Clinical meeting on April 20th
  • Dr Manuprasad attended “New Era in the management of head and neck cancer” Organized by Cancer Research and Statistics Foundation in Mumbai from July 11th and 12th as Faculty- Topic of presentation- Immune checkpoint inhibitors in Radioiodine refractory thyroid cancer
  • Dr Chandran K Nair attended KEM alumni meet  CME  and presented  “ approach to  newly diagnosed myeloma ”
  • Dr Jithin T K and Dr K G Gopakumar attended 7th Midterm CME of Pediatric hematology oncology chapter of IAP on 2nd and 3rd of July 2022 as faculty 
  • Dr Jithin T K was an invited speaker for the talk "Importance of well baby clinic in pediatric oncology" at the 7th Midterm CME of Pediatric hematology oncology chapter of IAP on 2nd and 3rd of July 2022  
  • Dr K G Gopakumar was an invited speaker for the talk "Initial stabilization of a child with suspected cancer" at the 7th Midterm CME of Pediatric hematology oncology chapter of IAP on 2nd and 3rd of July 2022 
  • Dr K G Gopakumar delivered a talk on " Childhood Cancers; How are they different ? " in the Nursing symposium and workshop conducted as part of the 7th Midterm CME of Pediatric hematology oncology chapter of IAP on 2nd July 2022 
  • Dr Manuprasad attended ESMO Advanced course on biomarkers for precision medicine held on Oct 9th and 10th at Singapore
  • Dr Manuprasad attended 20th annual conference of Women’s cancer Initiative -TMH as faculty October 14th-16th
  • Dr Manuprasad attended ISMPO ISO CON 2022 on Oct 29th-30th as faculty in Chennai
  • Dr Chandran K Nair attended Cancer consolidation annual meeting   October 20th -23 as faculty in Mumbai 
  • Dr Manuprasad attended in  association with Malabar  oncology club and association of medical and pediatric oncologists of kerala (Ampok) and KASO(Kerala association of  surgical  oncologist) conducted  urooncocon 2022 a national conference on recent  advances in urological cancer. 
  • Dr Manuprasad attended European Society Of Medical Oncology ASIA (ESMO ASIA) 2022 Conference in Singapore on Dec 2nd-5th and presented a poster and won the Best Abstract award in Genitourinary Cancer category (Title-Toxicity and Outcomes with Oral Fosfestrol in CRPC-Experience from a Low middle income country
  • Dr Manuprasad attended 6th Year End Review In Lung Cancer organized by Cancer Research and Statistics Foundation held at Mumbai on Dec 16th-18th as Faculty
  • Dr Jithin T K attended a training on infectious diseases in children with cancer at St Jude Children's research hospital, Memphis, USA as part of Global ID program. It was a 2 weeks program - 20/02/2023 - 04/03/2023.
     

  • An Audit of outcome patients with epidermal growth factor receptor mutations in non-squamous non-small cell lung cancer from a tertiary cancer center in Northern Kerala
  • A. phase1, open label first in human study investigating the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of HPK1 inhibitor GRC 54276 alone and in  combination with anti-PD-1 monoclonal antibody pembrolizumab or anti -PD-11 atezolizumab in subjects with advanced solid  tumors and Hodgkin’s lymphoma -PI(2 patients enrolled,1 patient being screened)PI
  • A  Multicenter Randomised , Double blind , Parallel,  Phase lll Global Study  to Assess the  Efficacy and  Safety of BP01 (Bevacizumab) when compared  to Avastin r-Eu  in combination with Carboplatin  and Paclitaxel during  induction  phase and  Bevacizumab alone  during  the maintenance phase in  patients with  newly diagnosed  or recurrent  Stage lllB/ IV  Non  Squamous (ns) Non- Small cell lung  cancer  (NSCLC)-PI(3 patients enrolled ,2 patients ongoing)PI
  • A phase3 study  of CCNU versus CCNU  plus  mebendazole in glioma - PI(IEC approved ,yet to start recruitment)
  • Treatment pattern and  outcomes if patient with NSCLC in  second -line setting-a multicentric study- PI(enrolled 10 patient, ongoing study, waiting for data from other center too)
  • Prospective ,multicenter ,open-label, phase IV ,interventional study to assess the safety and efficacy of Cap  imatinib in indian patients with mesenchymal epithelial transition (MET)exon 14 skipping mutation positive advanced non small cell lung cancer(NSCL)as PI(screened patients, currency protocol being amended) -PI
  • A Phase IV, prospective , multicenter, open label non -comparative interventional study to assess the safety of alpelisib plus fulvestrant , in men and post- menopausal women with HR-positive, HER2 -negative  advanced breast cancer (aBC) with PIK3CA mutation , whose disease has progressed on or after endocrine based  treatment (Screened 2, enrolled1)PI
  • Immunotherapy in Advanced solid Tumors- a  multicentric retrospective study from india (enrolled22 patient from our center ,overall about 600 patient )
  • Phase3 randomized study for evaluation of physician choice Rx and triple metronomic as second line therapy in head and neck cancer (investigation initiated multicenter trial-1 patient from mcc-ongoing ,total 114 patients completed  recruitment )
  • Efficacy of Pioglitazone in combination with neoadjuvant chemotherapy in patient with Extremity Skeletal High-Grade Osteosarcoma Treated with curative intent: An open -label, multi- center, randomized phase ii Clinical trial (IEC approved, yet to recruit)
  • A Randomized ,Multiple- dose, multicenter , comparative parallel study to evaluate the Pharmacokinetic, PHARMACOKINETIC,Efficiancy  and safety of  subcutaneous injection of denosumab(Hetero) and Reference medical product(Denosumab,amgen inc) un patients with bone metastases from solid tumors (Reapproved yet to start)
  • Quality of life outcome in cancer patients living with intestinal stoma A prospective cross- sectional study(enrolled 54 patients , interim abstract presented in a national conference by Dr Biji)
     

  • Oral metronomic chemotherapy as a feasible preoperative therapy in advanced resectable oral cavity squamous cell carcinomas – a preliminary experience. Shenoy V P Praveen Kumar, Manuprasad Avaronnan, Babu Sajith, Aravind Sithara, Narayanan Vinin N, Nayanar Sangeetha, Balasubramanian Satheesan ecancer 16 1425 (2022)
  • Utility of annual surveillance mammography in patients with treated breast cancer- A single Institutiona experience from India- Manuprasad A, Sreelakshmi Soman, Satheesh Babu TV, Geetha Muttath Onkologia i Radioterapia ( 2022) Volume 16, Issue 12
  • Praveen Kumar Shenoy VP, Raghavan V, Manuprasad A, Sajeev Kumar PB, Raj Z, Nair Fearof Recurrence and Somatic Symptom Severity in Multiple Myeloma Patients: An Institution - Based Cross-Sectional Study. Indian J Med Paediatr Oncol [Internet]. Thieme Medical Publishers, Inc.; 2022 Sep 1 [cited 2023 May 19];43(4):355–60. Available from: http://www.thieme-connect.de/products/ejournals/html/10.1055/s-0042-1755302
  • Sengar M, Korula A, Ganesan P, Rajendra A, Jain H, Samuel P, et al. Prognostic Factors and Outcomes of Adolescent and Adult Burkitt Lymphoma and Leukemia from a Low-Middle Income Country: An Experience from Hematology Cancer Consortium. Blood [Internet]. American Society of Hematology; 2022 Nov 15 [cited 2023 May 19];140(Supplement 1):6687–9. Available from: https://ashpublications.org/blood/article/140/Supplement   1/6687/487216/Prognostic-Factors-and-Outcomes-of-Adolescent-and
  • Raghavan V, Jithin TK, Gopakumar KG, Nandini Devi R, Manuprasad A, Shenoy PK, et al. Indications , outcome and cost implications of hematopoetic stem cell transplantation (HSCT)
  • in children - Experience from a public sector tertiary care centre in rural India. Pediatr
  • Hematol Oncol J. Elsevier; 2022 Jan 1;7(4):S24.
  • Nirmal G, Jithin TK, Gopakumar KG, Parthiban R, Nair C. Prevalence and Outcomes of Carbapenem-resistant Bloodstream Infection in Children with Cancer. Journal of Pediatric Hematology/Oncology. 2023 May 3:10-97.
  • Fear of Recurrence and Somatic Symptom Severity in Multiple Myeloma Patients: An Institution   Based Cross-Sectional Study . Praveen Kumar Shenoy V. P, Vineetha Raghavan, Avaronnan Manuprasad, Sajeev Kumar P. B. Zoheb Raj Chandran K. Nair Ind J Med Paediatr Oncol 2022;43:355–36.